Beyond C9orf72: repeat expansions and copy number variations as risk factors of amyotrophic lateral sclerosis across various populations
Abstract Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder which is characterized by the loss of both upper and lower motor neurons in the central nervous system.In a significant fraction of ALS cases - irrespective of family history- a genetic background may be identified.The genetic background of ALS shows a high variability fro